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Interest Subsequent Event Subsequent Events [Text Block] Fair value, assets, transfers into level 3 Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3 Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Expected volatility of underlying common stock Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Research and development Accrued research and development Accrued research and development Assets, Fair Value Disclosure [Abstract] Assets, Fair Value Disclosure [Abstract] Leiden Dworak [Member] Leiden Dworak. Leiden Dworak [Member] Risk free interest rate Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Schedule of Shares Reserved for Future Issuance Schedule of Common Stock Reserved for Future Issuance [Table Text Block] Schedule of common stock reserved for future issuance. 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Long-Term Debt Final Payment fee Plus: Final payment fee Compensation and benefits Employee-related Liabilities, Current, Total Employee-related Liabilities, Current Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Restructuring and Related Activities [Abstract] K2HV [Member] K2 Health Ventures. K2 Health Ventures [Member] Earnings Per Share [Abstract] Summary of Stock Option Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Plan Name Plan Name [Axis] Subsequent Event Type [Axis] License Initial Payment Received License initial payment received. License initial payment received Stockholders' Equity Equity [Text Block] Cash flows from financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Debt Instrument, Repaid, Principal Repaid remaining principal amount Date of incorporation Entity Incorporation, Date of Incorporation Entity Tax Identification Number Entity Tax Identification Number Equity Component Equity Component [Domain] Entity Address, City or Town Entity Address, City or Town Deferred revenue Increase (Decrease) in Contract with Customer, Liability Capital Expenditures Incurred but Not yet Paid Property and equipment included in accounts payable and accrued expenses 2027 Long-Term Debt, Maturity, Year One Issuance of common stock, net of offering cost/ ESPP plan Stock Issued During Period, Value, New Issues Issuance of common stock, net of offering costs Less: Restricted cash Restricted cash Lease security amount Segments [Domain] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Government Securities US Government Debt Securities [Member] Long-term deposits and other assets Long-term deposit Deposits Assets, Noncurrent Restructuring and Related Cost, Number of Positions Eliminated Work force reduction Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Purchases of marketable securities Purchases of marketable securities Payments to Acquire Marketable Securities Statement [Table] Statement [Table] Deferred Revenue, Current, Total Deferred revenue, current portion Deferred Revenue, Current Entity Shell Company Entity Shell Company Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash (used in) provided by investing activities Other Income and Expenses [Abstract] Other (expense) income: Statement [Line Items] Statement [Line Items] Long-term deferred revenue Deferred Revenue, Noncurrent, Total Deferred revenue, net of current portion Deferred Revenue, Noncurrent Prepayment fee range Percentage of Loan Prepayment Fee Range Percentage of Loan Prepayment Fee Range Prepayment fee range Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Commitments And Contingencies Disclosure [Table] Commitments And Contingencies Disclosure [Table] Commitments and contingencies disclosure. Unvested restricted stock, Vested Unvested restricted stock, Vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Maximum Maximum [Member] Convertible outstanding principal balance Debt Conversion, Original Debt, Amount Tranche 3. Tranche Three [Member] Debt Disclosure [Abstract] Sale of Stock Sale of Stock [Domain] Restricted stock, vesting term Share Based Compensation Arrangement By Share Based Payment Award Restricted Stock Vesting Term Share based compensation arrangement by share based payment award restricted stock vesting term. Schedule of share based compensation restricted common stock activity. Summary of Restricted Common Stock Activity Schedule Of Share Based Compensation Restricted Common Stock Activity Table [Text Block] Subsequent Events [Abstract] Tranche One [Member] Tranche One [Member] Minimum Bid Price Per Share Minimum bid price per share. Minimum bid price Facility-related and other Facility Related and Other Facility related and other. Restructuring Cost and Reserve [Line Items] Current assets: Assets, Current [Abstract] Consulting and professional fees Accrued Professional Fees, Current Common stock issuable upon exercise of stock options [Member] Common stock issuable upon exercise of stock options. Common stock issuable upon exercise of stock options Common Stock Issuable Upon Exercise of Stock Options Document Fiscal Year Focus Document Fiscal Year Focus Payments for Restructuring Cash payments Cash payments Sales Agreement. Sales Agreement [Member] ATM Program License upfront payment receivable. License upfront payment receivable Upfront payment receivable Common stock, shares outstanding Balances, shares Balances, shares Common Stock, Shares, Outstanding Prime Rate [Member] Common stock price per warrant. Common Stock Price Per Warrant Common stock price per warrant Underwriter option to purchase number of additional shares. Underwriter Option To Purchase Number Of Additional Shares Underwriter option to purchase number of additional shares Novartis Novartis [Member] Novartis. Restructuring Type [Axis] Maximum aggregate offering proceeds Maximum aggregate offering proceeds. Financial Instruments [Domain] Entity Ex Transition Period Entity Ex Transition Period Accrued severance Cost Accrued severance Cost. Accrued severance cost Operating lease liability, net of current portion Operating Lease, Liability, Noncurrent License initial payment receivable License initial payment receivable. 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Entity Address, State or Province Entity Address, State or Province Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Weighted average period remaining (in years) Series A Preferred Stock Series A Preferred Stock [Member] Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Issuance of common stock shares under the plan Operating lease assets Right-of-use assets Operating Lease, Right-of-Use Asset Amendment Flag Amendment Flag Stock Based Compensation Share-Based Payment Arrangement [Text Block] Debt Instrument [Axis] Total other (expense) income Other Nonoperating Income (Expense) Cash, cash equivalents and restricted cash at end of the period Cash, cash equivalents and restricted cash at beginning of the period Total cash, cash equivalents, and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Total cash, cash equivalents, and restricted cash Two Thousand Twenty Five Workforce Reduction [Member] Two thousand twenty five workforce reduction member. 2025 Workforce Reduction City Area Code City Area Code Interest only payment extended term. Interest Only Payment Extended Term Interest only payment extended term Issuance of common stock from employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Issuance of common stock under employee stock purchase plan Two Thousand Twenty Six Workforce Reduction [Member] Two thousand twenty six workforce reduction. 2026 Workforce Reduction Organization, Consolidation and Presentation of Financial Statements [Abstract] Non Rule 10b 51 Arr Modified Flag Non Rule 10b 51 Arr Modified Flag. Non-Rule 10b5-1 Arrangement Modified Expects research term Expects Research Term Expects research term. Issuance of common stock from employee stock purchase plan Proceeds from issuance of common stock, net of offering costs Proceeds from Issuance of Common Stock License upfront payment. License Upfront Payment Upfront payment Eurodollar [Member] Operating expenses: Less: Operating Expenses [Abstract] Common stock, par value Common Stock, Par or Stated Value Per Share Stock options exercisable, Weighted Average Remaining Contractual Life Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted-Average Remaining Contractual Term Stock Options vested or expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Total current liabilities Liabilities, Current Cash Equivalents - Government Securities US Government Corporations and Agencies Securities [Member] Liquidation Preference Temporary Equity, Liquidation Preference Collaboration and license agreements. 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Jason Amello [Member] Jason Amello. Final fee Final Fee Percentage Final Fee Percentage Final fee Document Information [Line Items] Document Information [Line Items] Segment Reporting [Abstract] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Statement of Financial Position [Abstract] 2018 Equity Incentive Plan Two Thousand And Eighteen Equity Incentive Plan [Member] 2018 equity incentive plan. Local Phone Number Local Phone Number Collaboration And License Revenue Collaboration and license revenue.